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The nuclear-cytoplasmic ratio (also variously known as the nucleus:cytoplasm ratio, nucleus-cytoplasm ratio, N:C ratio, or N/C) is a measurement used in cell biology. It is a ratio of the size (i.e., volume) of the nucleus of a cell to the size of the cytoplasm of that cell. The N:C ratio indicates the maturity of a cell, because as a cell matures the size of its nucleus generally decreases. So, for example, "blast" forms of erythrocytes, leukocytes, and megakaryocytes start with an N:C ratio of 4:1, which decreases as they mature to 2:1 or even 1:1 (with exceptions for mature thrombocytes and erythrocytes, which are anuclear cells, and mature lymphocytes, which only decrease to a 3:1 ratio and often retain the original 4:1 ratio).〔 An increased N:C ratio is commonly associated with precancerous dysplasia as well as with malignant cells. ==See also== *Cell growth#Yeast cell size regulation *Cytopathology *Nuclear atypia *Nuclear pleomorphism 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「NC ratio」の詳細全文を読む スポンサード リンク
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